The package, found on the seventh floor of 375 Greenwich St.in New York City's Tribeca neighborhood, was reported to police around 4:45 a.m.
U.S. authorities are searching for suspects in the sending of package bombs to high-profile Democrats in what's been called a terrorist act that's raised tensions in a nation already polarised ahead of elections in November.
X-ray images show that the package addressed to De Niro contains a device similar to the pipe bombs found in other packages this week that were addressed to prominent critics of Trump, the two sources said.
A supporter of the Democratic Party, De Niro has openly criticized Trump, saying he's "so blatantly stupid" and, onstage at the Tony's, "fuck Trump".
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The FBI says the packages are consistent with the ones sent to other leading Democrats. They came in brown envelopes with six stamps and the return address of Democratic lawmaker Debbie Wasserman Schultz.
An explosive ordnance disposal team destroyed the package sent to Soros through a controlled detonation.
The large investigation at the De Niro address caused nearby roads to be blocked until after sunrise Thursday.
None of the packages detonated, and nobody was injured.
Two more suspicious devices were intercepted on Thursday ー one in Delaware en route to former VP Joe Biden and the other at the restaurant and office of actor Robert De Niro in Lower Manhattan ー the eighth and ninth to be sent to high-profile critics of President Trump in a period of three days.
Joe Biden: Authorities are trying to track down a package addressed to the former vice president, two law enforcement sources told CNN's Josh Campbell and Brynn Gingras on Wednesday night.
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The bomb squad responded and removed the device, which was placed in an NYPD bomb vehicle to be taken to a safe area.
Democratic Representative Maxine Waters said in a statement on Wednesday that US Capitol Police said that her Washington, DC, office was the target of a suspicious package that was referred to the Federal Bureau of Investigation. The FBI is now seeking the perpetrator with a full-scale manhunt. Law enforcement authorities are treating the series of bombs as a domestic terror matter and are advising the public to remain vigilant.
At least eight parcels were intercepted before reaching any intended recipients, including Obama's attorney-general, Eric Holder, former Central Intelligence Agency director John Brennan and prominent Democratic Party donor George Soros.
"We will not rest until we find this suspect, stop these hazardous devices from being mailed, and bring this individual or individuals to justice", said FBI NYC Counterterror Chief Bryan Paarmann.
Sanders, speaking in an interview on Fox News, said the White House continued to condemn any attempted violence and would continue to direct federal resources toward the ongoing investigation.
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