Defeat ends Wenger's hopes of leaving Arsenal on a high as his team missed out on a shot at a major trophy and squandered their last chance to qualify for the Champions League.
Koscielny, 32, would have expected to be in France's squad for the World Cup in Russian Federation, but is now a major doubt and should Wenger's prediction prove correct, the defender could even miss the start of next season.
In truth, however, Arsenal's final pass was all too often lacking, and in the end they were unable to breach the home side's resolute defence.
Arsenal travelled to Atletico Madrid's Wanda Metropolitano knowing they needed to score at least once following Antoine Griezmann's away goal in last week's 1-1 draw at the Emirates.
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The deal must prevent Iran from becoming a nuclear threat, with stronger provisions in place to force them to keep their word. Russian Federation and Israel have conflicting interests in the delicately-balanced seven-year long Syrian Civil War.
We were 1-0 up at home and conceded a stupid goal. The game can be very cruel; sometimes it is very nice. 'Even very frustrated, as well, because when you go out of a competition and you had the performances in 180 minutes that we had, it very hard to take.
Wenger announced his decision to depart in April, after being in the job for almost 22 years and presiding over three Premier League title wins and seven FA Cup triumphs.
Simeone has now guided Atletico to a fourth European final in seven seasons in charge.
"I am like the team; very sad and very disappointed, even very frustrated, as well, because when you go out of a competition and you had the performances in the 180 minutes that we had, it is very hard to take".
The moment that sent Atleti to their third European final in four years was Diego Costa's late first-half goal.
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These purple crystals enable players to float in zero gravity for a limited time, opening up a whole host of gameplay options. Glowing shards of the crater are also scattered around the area, letting players "lift off with low gravity".
He said: "The risky situations were there but in the two boxes we missed something".
Wenger, in his 250th UEFA game as a club coach, announced two weeks ago he was standing down after almost 22 years with the London team.
The 32-year-old lost his footing while moving towards Diego Costa off the ball and was in obvious distress as he clutched his lower leg.
Arsenal striker Alexandre Lacazette posed a constant threat in the first 45 minutes and defender Hector Bellerin created danger with forays down the right side but without producing any change on the scoreboard.
Southwest jet diverted with cracked window
Flight passengers reported that a window on the plane had cracked. " We didn't know if it was going to crack open ". A Newark-bound Southwest Airlines flight made an emergency landing in Cleveland Wednesday after a window cracked.
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