A Met Office yellow warning for snow and ice has been issued for Central, Tayside and Fife, Grampian, the Highlands, the Western Isles, the Northern Isles, Strathclyde, the Borders and south-west Scotland.
Yellow "be aware" alerts have been put on place from 8am on Thursday until 6pm on Saturday with severe weather expected to cause widespread transport disruption.
Given its name by the UK Met Office, Storm Caroline is an Atlantic storm that is expected to pass close to the north coast of Scotland on Thursday morning, with strong and blustery winds also expected over Ireland later in the week.
Accumulations of snow of up to 3cm could fall in places on Thursday and Friday, forecasters have warned north and northwest counties will be "most at risk". As the storm moved away from the United Kingdom and towards Scandinavia on Friday it would be followed by cold air.
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'Overnight, the main feature will be the increase in wind as Caroline starts to come in towards the end of the night.
This will be followed by a day of "increasingly frequent" snow showers across Scotland which will affect most of the country, including parts of Tayside.
The Met Office said the high winds were expected to damage buildings and cause flying debris, as well as power cuts, severe travel disruption and unsafe waves.
Some roads and railways likely to be affected with longer journey times by road, bus and for train services.
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Friday will also be cold, Met Éireann said, with sunshine and scattered rain, hail, sleet and snow showers, and temperatures of 3 to 6 degrees in gusty northwesterly winds. Some short-term loss of power and other services is possible.
The Met Office said "predominantly colder periods" are expected through the second half of December until after Christmas, with snow in the Midlands and North.
Winds are forecast to strengthen across parts of Britain on Wednesday ahead of the arrival of Storm Caroline.
"Large waves are expected and beach material may be thrown onto coastal roads, sea fronts and properties".
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A snow-ice warning has been issued for Ireland for the coming days.
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